Dataset Information

Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes.

ABSTRACT: Over the past decade several studies have reported that the gut microbiomes of mammals with similar dietary niches exhibit similar compositional and functional traits. However, these studies rely heavily on samples from captive individuals and often confound host phylogeny, gut morphology, and diet. To more explicitly test the influence of host dietary niche on the mammalian gut microbiome we use 16S rRNA gene amplicon sequencing and shotgun metagenomics to compare the gut microbiota of 18 species of wild non-human primates classified as either folivores or closely related non-folivores, evenly distributed throughout the primate order and representing a range of gut morphological specializations. While folivory results in some convergent microbial traits, collectively we show that the influence of host phylogeny on both gut microbial composition and function is much stronger than that of host dietary niche. This pattern does not result from differences in host geographic location or actual dietary intake at the time of sampling, but instead appears to result from differences in host physiology. These findings indicate that mammalian gut microbiome plasticity in response to dietary shifts over both the lifespan of an individual host and the evolutionary history of a given host species is constrained by host physiological evolution. Therefore, the gut microbiome cannot be considered separately from host physiology when describing host nutritional strategies and the emergence of host dietary niches.

SUBMITTER: Amato KR

PROVIDER: S-EPMC6461848 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes.

Amato Katherine R KR G Sanders Jon J Song Se Jin SJ Nute Michael M Metcalf Jessica L JL Thompson Luke R LR Morton James T JT Amir Amnon A J McKenzie Valerie V Humphrey Gregory G Gogul Grant G Gaffney James J L Baden Andrea A A O Britton Gillian G P Cuozzo Frank F Di Fiore Anthony A J Dominy Nathaniel N L Goldberg Tony T Gomez Andres A Kowalewski Martin M MM J Lewis Rebecca R Link Andres A L Sauther Michelle M Tecot Stacey S A White Bryan B E Nelson Karen K M Stumpf Rebecca R Knight Rob R R Leigh Steven S

The ISME journal 20180711 3

Over the past decade several studies have reported that the gut microbiomes of mammals with similar dietary niches exhibit similar compositional and functional traits. However, these studies rely heavily on samples from captive individuals and often confound host phylogeny, gut morphology, and diet. To more explicitly test the influence of host dietary niche on the mammalian gut microbiome we use 16S rRNA gene amplicon sequencing and shotgun metagenomics to compare the gut microbiota of 18 speci ...[more]

PMID: 29995839

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Dataset Information

Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes.

Publications

Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes.

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