Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia.
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ABSTRACT:
SUBMITTER: Barber S
PROVIDER: S-EPMC6464566 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia.
Barber Sarah S Olotu Uwaila U Corsi Martina M Cipriani Andrea A
The Cochrane database of systematic reviews 20170323
<h4>Background</h4>Between 40% and 70% of people with treatment-resistant schizophrenia do not respond to clozapine, despite adequate blood levels. For these people, a number of treatment strategies have emerged, including the prescription of a second anti-psychotic drug in combination with clozapine.<h4>Objectives</h4>To determine the clinical effects of various clozapine combination strategies with antipsychotic drugs in people with treatment-resistant schizophrenia both in terms of efficacy a ...[more]
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