Hypothalamic-Pituitary-Ovarian Axis Disorders Impacting Female Fertility.
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ABSTRACT:
SUBMITTER: Mikhael S
PROVIDER: S-EPMC6466056 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Hypothalamic-Pituitary-Ovarian Axis Disorders Impacting Female Fertility.
Mikhael Sasha S Punjala-Patel Advaita A Gavrilova-Jordan Larisa L
Biomedicines 20190104 1
The hypothalamic-pituitary-ovarian (HPO) axis is a tightly regulated system controlling female reproduction. HPO axis dysfunction leading to ovulation disorders can be classified into three categories defined by the World Health Organization (WHO). Group I ovulation disorders involve hypothalamic failure characterized as hypogonadotropic hypogonadism. Group II disorders display a eugonadal state commonly associated with a wide range of endocrinopathies. Finally, group III constitutes hypergonado ...[more]
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