Comparison of the prevalence, severity, and risk factors for hepatic steatosis in HIV-infected and uninfected people.

ABSTRACT:

Background

Hepatic steatosis is prevalent in Western countries, but few studies have evaluated whether the frequency and severity of steatosis are greater in the setting of HIV infection. We compared the prevalence and severity of hepatic steatosis between HIV-infected (HIV+) and uninfected persons and identified factors associated with greater steatosis severity within both groups.

Methods

We performed a cross-sectional study among participants without cardiovascular disease who participated in a substudy of the Veterans Aging Cohort Study. Hepatic steatosis was defined by noncontrast computed tomography (CT) liver-to-spleen (L/S) attenuation ratio < 1.0. Multivariable linear regression was used to: 1) evaluate the association between HIV infection and severity of hepatic s

SUBMITTER: Torgersen J 

PROVIDER: S-EPMC6466708 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature