Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC6466712 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Liu Yansong Y Fu Xiaoqian X Tang Zhen Z Li Cui C Xu Yong Y Zhang Fuquan F Zhou Deyi D Zhu Chunming C
BMC psychiatry 20190415 1
<h4>Background</h4>Schizophrenia (SCZ) is a heritable, refractory, and devastating psychiatric disorder. Previous studies have shown that the variants of CUB and sushi multiple domains 1 (CSMD1) demonstrate significant genome-wide association with SCZ. However, few studies have been conducted on the effect of antipsychotics on the expression levels of CSMD1. This study explored whether a change occurs in the expression of the CSMD1 gene before and after antipsychotic treatment in SCZ patients.<h ...[more]