Ontology highlight
ABSTRACT:
SUBMITTER: Chakraborty S
PROVIDER: S-EPMC6466737 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
ACS catalysis 20181002 11
Herein we report the manganese-catalyzed C-C bond-forming reactions via α-alkylation of ketones, amides, and esters, using primary alcohols. β-Alkylation of secondary alcohols by primary alcohols to obtain α-alkylated ketones is also reported. The reactions are catalyzed by a ( <sup><i>i</i></sup> Pr-PNP)Mn(H)(CO)<sub>2</sub> pincer complex under mild conditions in the presence of (catalytic) base liberating water (and H<sub>2</sub> in the case of secondary alcohol alkylation) as the sole byprod ...[more]