Ontology highlight
ABSTRACT:
SUBMITTER: Liu R
PROVIDER: S-EPMC6467982 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Liu Ran R Greenstein Joseph L JL Granite Stephen J SJ Fackler James C JC Bembea Melania M MM Sarma Sridevi V SV Winslow Raimond L RL
Scientific reports 20190416 1
Septic shock is a life-threatening condition in which timely treatment substantially reduces mortality. Reliable identification of patients with sepsis who are at elevated risk of developing septic shock therefore has the potential to save lives by opening an early window of intervention. We hypothesize the existence of a novel clinical state of sepsis referred to as the "pre-shock" state, and that patients with sepsis who enter this state are highly likely to develop septic shock at some future ...[more]