Ontology highlight
ABSTRACT:
SUBMITTER: Hou J
PROVIDER: S-EPMC6468356 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Hou Jingtong J Cong Ruth R Izumi-Willcoxon Michi M Ali Hana H Zheng Yi Y Bermudez Ericka E McDonald Mark M Nelson Mark M Yamamoto Takashi T
Toxins 20190314 3
A novel <i>Bacillus thuringiensis</i> Cry protein, Cry8Hb, active against <i>Diabrotica virgifera virgifera</i> (Western corn rootworm, WCRW) was discovered. Unexpectedly, the anti-rootworm activity of the Cry8Hb toxin was enhanced significantly by fusing <i>Escherichia coli</i> maltose binding protein (MBP) to this Cry toxin. While the exact mechanism of the activity enhancement remains indefinite, it is probable that the enhancement is a result of increased solubility of the MBP-Cry8Hb fusion ...[more]