Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC6468389 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Liu Xiangyang X Fang Wei W Fan Rui R Zhang Linna L Lei Chengfeng C Zhang Jingjing J Nian Wenkai W Dou Tao T An Shiheng S Zhou Lin L Sun Xiulian X
Toxins 20190304 3
The <i>Cydia pomonella granulovirus</i> (CpGV) GP37 has synergistic effects on the infectivity of <i>nucleopolyhedroviruses</i> (NPVs), however, the mechanism employed is unclear. In this study, in vitro and in vivo binding assays indicated that GP37 efficiently bound to the midgut peritrophic membrane (PM) of <i>Spodoptera exigua</i> larvae. Treatment with GP37 led to the damage of the PM's compacted structure and the generation of the PM perforations, and the enhancement of the PM's permeabili ...[more]