Ontology highlight
ABSTRACT:
SUBMITTER: Kalogeropoulos K
PROVIDER: S-EPMC6468401 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Kalogeropoulos Konstantinos K Treschow Andreas Frederik AF Auf dem Keller Ulrich U Escalante Teresa T Rucavado Alexandra A Gutiérrez José María JM Laustsen Andreas Hougaard AH Workman Christopher T CT
Toxins 20190319 3
Snake venom metalloproteinases (SVMPs) and snake venom serine proteinases (SVSPs) are among the most abundant enzymes in many snake venoms, particularly among viperids. These proteinases are responsible for some of the clinical manifestations classically seen in viperid envenomings, including hemorrhage, necrosis, and coagulopathies. The objective of this study was to investigate the enzymatic activities of these proteins using a high-throughput peptide library to screen for the proteinase targe ...[more]