Ontology highlight
ABSTRACT:
SUBMITTER: Le Vasseur M
PROVIDER: S-EPMC6468579 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Le Vasseur Maxence M Chen Vincent C VC Huang Kate K Vogl Wayne A WA Naus Christian C CC
Cancers 20190311 3
Endomembrane specialization allows functional compartmentalization but imposes physical constraints to information flow within the cell. However, the evolution of an endomembrane system was associated with the emergence of contact sites facilitating communication between membrane-bound organelles. Contact sites between the endoplasmic reticulum (ER) and mitochondria are highly conserved in terms of their morphological features but show surprising molecular diversity within and across eukaryote s ...[more]