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ABSTRACT: Objectives
To evaluate whether the Walking Impairment Questionnaire score could identify patients with polyvascular disease in a population with recent myocardial infarction and their association with cardiovascular events during two-year follow-up.Design
A prospective observational study.Setting
Patients admitted to the acute coronary care unit, the Department of Cardiology, Uppsala University Hospital.Participants
Patients admitted with acute Non-STEMI- or STEMI-elevation myocardial infarction.Main outcome measures
The Walking Impairment Questionnaire, developed as a self-administered instrument to assess walking distance, speed, and stair climbing in patients with peripheral artery disease, predicts future cardiovascular events and mortality. Two hundred and sixty-three patients with recent myocardial infarction answered Walking Impairment Questionnaire. Polyvascular disease was defined as abnormal findings in the coronary- and carotid arteries and an abnormal ankle-brachial index. The calculated score for each of all three categories were divided into quartiles with the lowest score in first quartile.Results
The lowest (worst) quartile in all three Walking Impairment Questionnaire categories was associated with polyvascular disease, fully adjusted; distance, odds ratio (OR) 5.4 (95% confidence interval (CI) 1.8-16.1); speed, OR 7.4 (95% CI 1.5-36.5); stair climbing, OR 8.4 (95% CI 1.0-73.6). In stair climbing score, patients with the lowest (worst) score had a higher risk for the composite cardiovascular endpoint compared to the highest (best) score; hazard ratio 5.3 (95% CI 1.5-19.0). The adherence to medical treatment was high (between 81.7% and 99.2%).Conclusions
The Walking Impairment Questionnaire is a simple tool to identify myocardial infarction patients with more widespread atherosclerotic disease and although well treated medically, stair climbing predicts cardiovascular events.
SUBMITTER: Jonelid B
PROVIDER: S-EPMC6469275 | biostudies-literature | 2019 Jan-Dec
REPOSITORIES: biostudies-literature
Jönelid Birgitta B Kragsterman Björn B Berglund Lars L Andrén Bertil B Johnston Nina N Lindahl Bertil B Oldgren Jonas J Christersson Christina C
JRSM cardiovascular disease 20190101
<h4>Objectives</h4>To evaluate whether the Walking Impairment Questionnaire score could identify patients with polyvascular disease in a population with recent myocardial infarction and their association with cardiovascular events during two-year follow-up.<h4>Design</h4>A prospective observational study.<h4>Setting</h4>Patients admitted to the acute coronary care unit, the Department of Cardiology, Uppsala University Hospital.<h4>Participants</h4>Patients admitted with acute Non-STEMI- or STEMI ...[more]