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A note on the relationship between age and health-related quality of life assessment.

ABSTRACT: PURPOSE:To extend existing analyses of whether and how the age of respondents is related to their time trade-off (TTO) valuations of hypothetical EQ-5D-3L health states, and to contribute to the existing debate about the rationale and implications for using age-specific utilities in health technology assessment (HTA). METHODS:We use data from the MVH UK valuation study. For each profile, the mean TTO value-adjusted by sex, education, self-reported health and personal experience of serious illness-is pairwise compared across the different age groups. A Bonferroni correction is applied to the multiple testing of significant differences between means. Smile plots illustrate the results. A debate regarding whether there is a case for using age-specific utilities in HTAs complements the analysis. RESULTS:Results show that the oldest respondents value health profiles lower than younger age groups, particularly for profiles describing problems in the mobility dimension. CONCLUSION:The findings raise the possibility of using age-specific value sets in HTAs, since a technology may not be cost-effective on average but cost-effective for a sub-group whose preferences are more closely aligned to the benefits offered by the technology.

SUBMITTER: Cubi-Molla P

PROVIDER: S-EPMC6470117 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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A note on the relationship between age and health-related quality of life assessment.

Cubi-Molla Patricia P Shah Koonal K Garside Jamie J Herdman Mike M Devlin Nancy N

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20181206 5

<h4>Purpose</h4>To extend existing analyses of whether and how the age of respondents is related to their time trade-off (TTO) valuations of hypothetical EQ-5D-3L health states, and to contribute to the existing debate about the rationale and implications for using age-specific utilities in health technology assessment (HTA).<h4>Methods</h4>We use data from the MVH UK valuation study. For each profile, the mean TTO value-adjusted by sex, education, self-reported health and personal experience of ...[more]

PMID: 30523567

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A note on the relationship between age and health-related quality of life assessment.

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A note on the relationship between age and health-related quality of life assessment.

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