Galectin-3 and ?-trace protein concentrations are higher in clinically unaffected patients with Fabry disease.
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ABSTRACT:
SUBMITTER: Hernandez-Romero D
PROVIDER: S-EPMC6470309 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
Galectin-3 and β-trace protein concentrations are higher in clinically unaffected patients with Fabry disease.
Hernández-Romero Diana D Sánchez-Quiñones Jessica J Vílchez Juan Antonio JA Rivera-Caravaca José Miguel JM de la Morena Gonzalo G Lip Gregory Y H GYH Climent Vicente V Marín Francisco F
Scientific reports 20190417 1
Current therapies have not shown benefit in organ damage reversal in Fabry disease (FD), but biomarkers could help risk stratification and prognosis. We investigated if several biomarkers of cardiac fibrosis, cardiac wall stress, myocardial injury, renal function and inflammation, are associated with early cardiac affectation in FD patients. We included FD patients from four cardiology outpatient clinics of southeastern Spain. At inclusion, Galectin-3 (Gal-3), N-terminal proB-type natriuretic pe ...[more]
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