Associations between brain structure and perceived intensity of sweet and bitter tastes.

ABSTRACT: Functional neuroimaging studies have identified brain regions associated with human taste perception, but only a few have investigated the associations with brain structure. Here, in this exploratory study, we examined the association between the volumes of 82 regions of interest (ROI) and the perceived intensities of sweet (a weighted mean rating of glucose, fructose, aspartame, neohesperidin dihydrochalcone) and bitter (propylthiouracil, quinine, caffeine) substances in a large Australian healthy cohort from the Queensland Twin IMaging (QTIM, n?=?559) study and the perceived intensity of quinine in a large U.S. healthy cohort from the Human Connectome Project (HCP, n?=?1101). In QTIM, the volumes of 3 cortical (right cuneus gyrus, left transverse temporal gyrus, right inferior temporal gyrus) and one subcortical structure (both left and right caudate) were associated with more than one taste stimulus (P?

SUBMITTER: Hwang LD 

PROVIDER: S-EPMC6470356 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature