Ontology highlight
ABSTRACT:
SUBMITTER: Ankavay M
PROVIDER: S-EPMC6472401 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Ankavay Maliki M Montpellier Claire C Sayed Ibrahim M IM Saliou Jean-Michel JM Wychowski Czeslaw C Saas Laure L Duvet Sandrine S Aliouat-Denis Cécile-Marie CM Farhat Rayan R de Masson d'Autume Valentin V Meuleman Philip P Dubuisson Jean J Cocquerel Laurence L
Scientific reports 20190418 1
Hepatitis E Virus (HEV) genome encodes three proteins including the ORF2 capsid protein. Recently, we demonstrated that HEV produces three different forms of ORF2: (i) the ORF2i form (infectious ORF2) which is the component of infectious particles, (ii) the secreted ORF2g (glycosylated ORF2) and ORF2c (cleaved ORF2) forms that are not associated with infectious particles, but are the major antigens in HEV-infected patient sera. The ORF2 protein sequence contains three highly conserved potential ...[more]