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Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus.


ABSTRACT:

SUBMITTER: Madsen KS 

PROVIDER: S-EPMC6472662 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus.

Madsen Kasper S KS   Kähler Pernille P   Kähler Lise Katrine Aronsen LKA   Madsbad Sten S   Gnesin Filip F   Metzendorf Maria-Inti MI   Richter Bernd B   Hemmingsen Bianca B  

The Cochrane database of systematic reviews 20190418


<h4>Background</h4>The number of people with type 2 diabetes mellitus (T2DM) is increasing worldwide. The combination of metformin and sulphonylurea (M+S) is a widely used treatment. Whether M+S shows better or worse effects in comparison with other antidiabetic medications for people with T2DM is still controversial.<h4>Objectives</h4>To assess the effects of metformin and sulphonylurea (second- or third-generation) combination therapy for adults with type 2 diabetes mellitus.<h4>Search methods  ...[more]

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