Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring.

ABSTRACT: Human health is dependent upon environmental exposures, yet the diversity and variation in exposures are poorly understood. We developed a sensitive method to monitor personal airborne biological and chemical exposures and followed the personal exposomes of 15 individuals for up to 890 days and over 66 distinct geographical locations. We found that individuals are potentially exposed to thousands of pan-domain species and chemical compounds, including insecticides and carcinogens. Personal biological and chemical exposomes are highly dynamic and vary spatiotemporally, even for individuals located in the same general geographical region. Integrated analysis of biological and chemical exposomes revealed strong location-dependent relationships. Finally, construction of an exposome interaction

SUBMITTER: Jiang C 

PROVIDER: S-EPMC6472932 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature