Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging.
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ABSTRACT:
SUBMITTER: Hou W
PROVIDER: S-EPMC6472954 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging.
Hou Weijia W Liu Yuan Y Liu Yuan Y Jiang Ying Y Wu Yuan Y Cui Cheng C Wang Yanyue Y Zhang Liqin L Teng I-Ting IT Tan Weihong W
Nanoscale 20180601 23
We designed an aptamer-based multifunctional ligand which, upon conjugation to the surface of upconversion nanoparticles (UCNPs), could realize phase transfer, covalent photosensitizer (PS) loading, and cancer cell targeting in one simple step. The as-built PDT nanodrug is selectively internalized into cancer cells and it exhibits highly efficient and selective cytotoxicity. ...[more]
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