Ontology highlight
ABSTRACT:
SUBMITTER: Jiang L
PROVIDER: S-EPMC6473039 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Jiang Liang L Liu Weiqiang W Guo Huizhen H Dang Yinghui Y Cheng Tingcai T Yang Wanying W Sun Qiang Q Wang Bingbing B Wang Yumei Y Xie Enyu E Xia Qingyou Q
Frontiers in immunology 20190412
Peptidoglycan recognition protein (PGRP) is an important pattern recognition receptor in innate immunity that is vital for bacterial recognition and defense in insects. Few studies report the role of PGRP in viral infection. Here we cloned two forms of PGRP from the model lepidopteran <i>Bombyx mori</i>: BmPGRP2-1 is a transmembrane protein, whereas BmPGRP2-2 is an intracellular protein. BmPGRP2-1 bound to diaminopimelic acid (DAP)-type peptidoglycan (PGN) to activate the canonical immune defici ...[more]