Ontology highlight
ABSTRACT:
SUBMITTER: Garrido-Jimenez S
PROVIDER: S-EPMC6473044 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Garrido-Jimenez Sergio S Roman Angel-Carlos AC Carvajal-Gonzalez Jose Maria JM
Frontiers in genetics 20190412
Proper ciliary basal body positioning within a cell is key for cilia functioning. Centriole and basal body positioning depends on signaling pathways such as the planar cell polarity pathway (PCP) governed by Frizzled (Fz-PCP). There have been described two PCP pathways controlled by different protein complexes, the Frizzled-PCP and the Fat-PCP pathway. Centriole planar polarization in non-dividing cells is a dynamic process that depends on the Fz-PCP pathway to properly occur during development ...[more]