Controlled Electron-Beam Synthesis of Transparent Hydrogels for Drug Delivery Applications.

ABSTRACT: In this study, we highlight hydrogels prepared by electron-beam polymerization. In general, the electron-beam-polymerized hydrogels showed improved mechanical and optical transmittances compared to the conventional UV-cured hydrogels. They were more elastic and had a higher crosslinking density. Additionally, they were transparent over a broader wavelength range. The dependence of the mechanical and optical properties of the hydrogels on the number of single differential and total irradiation doses was analyzed in detail. The hydrogels were prepared for usage as a drug delivery material with methylene blue as a drug model. In the first set of experiments, methylene blue was loaded reversibly after the hydrogel synthesis. Electron-beam-polymerized hydrogels incorporated twice as much methyl

SUBMITTER: Glass S 

PROVIDER: S-EPMC6473313 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature