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Admission Heart Rate Variability is Associated with Fever Development in Patients with Intracerebral Hemorrhage.


ABSTRACT:

Background

Fever is associated with worse outcome after intracerebral hemorrhage (ICH). Autonomic dysfunction, commonly seen after brain injury, results in reduced heart rate variability (HRV). We sought to investigate whether HRV was associated with the development of fever in patients with ICH.

Methods

We prospectively enrolled consecutive patients with spontaneous ICH in a single-center observational study. We included patients who presented directly to our emergency department after symptom onset, had a 10-second electrocardiogram (EKG) performed within 24 h of admission, and were in sinus rhythm. Patient temperature was recorded every 1-4 h. We defined being febrile as having a temperature of ≥ 38 °C within the first 14 days, and fever burden as the number of febrile da

SUBMITTER: Swor DE 

PROVIDER: S-EPMC6474355 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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