Impact of malaria and hepatitis B co-infection on clinical and cytokine profiles among pregnant women.

ABSTRACT:

Background

The overlap of malaria and chronic hepatitis B (CHB) is common in endemic regions, however, it is not known if this co-infection could adversely influence clinical and immunological responses. This study investigated these interactions in pregnant women reporting to antenatal clinics in Ghana.

Methods

Clinical parameters (hemoglobin, liver function biomarker, peripheral malaria parasitemia, and hepatitis B viremia) and cytokine profiles were assayed and compared across four categories of pregnant women: un-infected, mono-infected with Plasmodium falciparum (Malaria group), mono-infected with chronic hepatitis B virus (CHB group) and co-infected (Malaria+CHB group).

Results

Women with Malaria+CHB maintained appreciably normal hemoglobin levels (mean±SEM = 10

SUBMITTER: Anabire NG 

PROVIDER: S-EPMC6474591 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature