Ontology highlight
ABSTRACT:
SUBMITTER: Nakayama Y
PROVIDER: S-EPMC6474599 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Nakayama Yujiro Y Iijima Takeru T Wakaume Rika R Takahashi Keiichi K Matsumoto Hiroshi H Nakano Daisuke D Miyaki Michiko M Yamaguchi Tatsuro T
PloS one 20190419 4
<h4>Background</h4>Microsatellite instability (MSI) is a clonal change in the number of repeated DNA nucleotide units in microsatellites. High-frequency MSI (MSI-H) colorectal cancers (CRCs) are known to have different clinicopathological features compared with microsatellite stable (MSS) CRCs. In addition, previous studies have shown that type2 diabetes mellitus (T2DM) is a risk factor for malignant tumors including CRCs. The aim of this study was to investigate the relationship between T2DM an ...[more]