Dataset Information

Associations between lipid profiles of adolescents and their mothers based on a nationwide health and nutrition survey in South Korea.

ABSTRACT:

Objectives

Dyslipidaemia is a metabolic disease influenced by environmental and genetic factors. Especially, family history related to genetic background is a strong risk factor of lipid abnormality. The aim of this study is to evaluate the association between the lipid profiles of adolescents and their mothers.

Design

A cross-sectional study.

Setting

The data were derived from the Korea National Health and Nutrition Examination Survey (IV-VI) between 2009 and 2015.

Participants

2884 adolescents aged 12-18 years and their mothers were included.

Primary outcome measures

Outcome variables were adolescents' lipid levels. Mothers' lipid levels were the interesting variables. The lipid profiles included total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). We identified partial correlation coefficients (r) between the lipids. Multiple linear regressions were performed to identify the amount of change in adolescents' lipid levels for each unit increase of their mothers' lipids. The regression models included various clinical characteristics and health behavioural factors of both adolescents and mothers.

Results

The mean levels of adolescents' lipids were 156.6, 83.6, 50.4 and 89.4?mg/dL, respectively for TC, TG, HDL-C and LDL-C. Positive correlations between lipid levels of adolescents and mothers were observed for TC, TG, HDL-C and LDL-C (r, 95% CI: 0.271, 0.236 to 0.304; 0.204, 0.169 to 0.239; 0.289, 0.255 to 0.322; and 0.286, 0.252 to 0.319). The adolescent TC level was increased by 0.23?mg/dL for each unit increase of the mother's TC (SE, 0.02; p<0.001). The beta coefficients were 0.16 (SE, 0.01), 0.24 (SE, 0.02) and 0.24 (SE, 0.02), respectively, in each model of TG, HDL-C and LDL-C (all p<0.001). The linear relationships were significant regardless of sex and mother's characteristics.

Conclusions

Mothers' lipid levels are associated with adolescents' lipids; therefore, they can serve as a reference for the screening of adolescent's dyslipidaemia.

SUBMITTER: Nam JH

PROVIDER: S-EPMC6475165 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Associations between lipid profiles of adolescents and their mothers based on a nationwide health and nutrition survey in South Korea.

Nam Ji Hyung JH Shin Jaeyong J Jang Sung-In SI Kim Ji Hyun JH Han Kyu-Tae KT Lee Jun Kyu JK Lim Yun Jeong YJ Park Eun-Cheol EC

BMJ open 20190320 3

<h4>Objectives</h4>Dyslipidaemia is a metabolic disease influenced by environmental and genetic factors. Especially, family history related to genetic background is a strong risk factor of lipid abnormality. The aim of this study is to evaluate the association between the lipid profiles of adolescents and their mothers.<h4>Design</h4>A cross-sectional study.<h4>Setting</h4>The data were derived from the Korea National Health and Nutrition Examination Survey (IV-VI) between 2009 and 2015.<h4>Part ...[more]

PMID: 30898813

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Dataset Information

Associations between lipid profiles of adolescents and their mothers based on a nationwide health and nutrition survey in South Korea.

Objectives

Design

Setting

Participants

Primary outcome measures

Results

Conclusions

Publications

Associations between lipid profiles of adolescents and their mothers based on a nationwide health and nutrition survey in South Korea.

Similar Datasets

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