Ontology highlight
ABSTRACT:
SUBMITTER: Jevtic P
PROVIDER: S-EPMC6476522 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Jevtić Predrag P Mukherjee Richik N RN Chen Pan P Levy Daniel L DL
PloS one 20190422 4
More than just a container for DNA, the nuclear envelope carries out a wide variety of critical and highly regulated cellular functions. One of these functions is nuclear import, and in this study we investigate how altering the levels of nuclear transport factors impacts developmental progression and organismal size. During early Xenopus laevis embryogenesis, the timing of a key developmental event, the midblastula transition (MBT), is sensitive to nuclear import factor levels. How might alteri ...[more]