Dataset Information

Economic Evaluation of Interventions in Parkinson's Disease: A Systematic Literature Review.

ABSTRACT:

Background

Parkinson's disease (PD) management comprises of drug treatments, surgery, and physical activity/occupational therapies to relieve PD's symptoms. The aim of this study is twofold; first, to appraise recent economic evaluation studies on PD management in order to update the existing knowledge; and second, to facilitate decision making on PD management by assessing the cost-effectiveness of all types of PD interventions.

Methods

A systematic search for studies published between 2010 and 2018 was conducted. The inclusion and exclusion of the articles were based on criteria relevant to population, intervention, comparison, outcomes, and study design (PICO). The reporting quality of the articles was assessed according to Consolidated Health Economic Evaluation Reporting Standards.

Results

Twenty-eight articles were included, 10 of which were evaluations of drug treatments, 10 deep brain stimulation (DBS), and eight physical/occupational therapies. Among early-stage treatments, Ti Ji dominated all physical activity interventions; however, its cost-effectiveness should be further explored in relation to its duration, intensity, and frequency. Multidisciplinary interventions of joint medical and nonmedical therapies provided slightly better health outcomes for the same costs. In advanced PD patients, adjunct drug treatments could become more cost-effective if introduced during early PD and, although DBS was more cost-effective than adjunct drug therapies, the results were time-bound.

Conclusions

Conditionally, certain PD interventions are cost-effective. However, PD progression differs in each patient; thus, the cost-effectiveness of individually tailored combinations of interventions that could provide more time in less severe disease states and improve patients' and caregivers' quality of life, should be further explored.

SUBMITTER: Afentou N

PROVIDER: S-EPMC6476603 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Publications

Economic Evaluation of Interventions in Parkinson's Disease: A Systematic Literature Review.

Afentou Nafsika N Jarl Johan J Gerdtham Ulf-G UG Saha Sanjib S

Movement disorders clinical practice 20190411 4

<h4>Background</h4>Parkinson's disease (PD) management comprises of drug treatments, surgery, and physical activity/occupational therapies to relieve PD's symptoms. The aim of this study is twofold; first, to appraise recent economic evaluation studies on PD management in order to update the existing knowledge; and second, to facilitate decision making on PD management by assessing the cost-effectiveness of all types of PD interventions.<h4>Methods</h4>A systematic search for studies published b ...[more]

PMID: 31061835

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Dataset Information

Economic Evaluation of Interventions in Parkinson's Disease: A Systematic Literature Review.

Background

Methods

Results

Conclusions

Publications

Economic Evaluation of Interventions in Parkinson's Disease: A Systematic Literature Review.

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