Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation.
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ABSTRACT:
SUBMITTER: Grade CVC
PROVIDER: S-EPMC6477727 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation.
Grade Carla Vermeulen Carvalho CVC Mantovani Carolina Stefano CS Alvares Lúcia Elvira LE
Journal of animal science and biotechnology 20190423
Myostatin (MSTN) is one of the key factors regulating myogenesis. Because of its role as a negative regulator of muscle mass deposition, much interest has been given to its protein and, in recent years, several studies have analysed <i>MSTN</i> gene regulation. This review discusses the <i>MSTN</i> gene promoter, focusing on its structure in several animal species, both vertebrate and invertebrate. We report the important binding sites considering their degree of phylogenetic conservation and ro ...[more]
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