Several circulating miRNAs related to hyperlipidemia and atherosclerotic cardiovascular diseases.

ABSTRACT:

Background

In recent years, an increasing number of studies have proved that circulating miRNAs could be used for the early diagnosis of cardiovascular diseases and even play vital roles in the evaluation of therapeutic effects or prognosis. This study was conducted to examine the correlation between serum microRNAs and hyperlipidemia to provide a theoretical basis for the early screening and intervention of atherosclerotic cardiovascular diseases (ASCVD).

Methods

The serum samples and clinical data of 122 patients with hyperlipidemia and 168 healthy subjects were collected. Related clinical information was statistically analyzed for the two groups. Expression of circulating miRNAs was detected by miRNA microarray analysis and further verified by reverse transcription-quanti

SUBMITTER: Xu J 

PROVIDER: S-EPMC6477752 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature