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ABSTRACT: Purpose
Evaluation of the usefulness of air as a negative contrast medium of blood vessels in goats in post mortem computed tomography (PMCT) and establishing the protocol with appropriate doses and timing of the contrast medium administration.Methods
Thirty three goats were euthanized 10 to 300 min before the study. First, in 3 goats air was administered into the left or right common carotid artery at dose of 60, 100 and 120 ml/kg, and after each dose PMCT was performed in lateral recumbency. As the latter dose proved to visualize blood vessels best, following 30 goats were examined in the same manner but only with the use of air dose of 120 ml/kg. The quality of CT scans was evaluated independently by two board-certified radiologists.Results
In all studied animals the vascular system filled with air was clearly visualized on CT scans. In most of goats this amount of air revealed vessels smaller than 4 mm in diameter.Conclusions
PMCT with air as a negative contrast agent may be an alternative technique used in post-mortem angiography.
SUBMITTER: Szalus-Jordanow O
PROVIDER: S-EPMC6478312 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Szaluś-Jordanow Olga O Bonecka Joanna J Pankowski Filip F Barszcz Karolina K Tarka Sylwia S Kwiatkowska Magdalena M Polguj Michał M Mickiewicz Marcin M Moroz Agata A Czopowicz Michał M Frymus Tadeusz T Kaba Jarosław J
PloS one 20190423 4
<h4>Purpose</h4>Evaluation of the usefulness of air as a negative contrast medium of blood vessels in goats in post mortem computed tomography (PMCT) and establishing the protocol with appropriate doses and timing of the contrast medium administration.<h4>Methods</h4>Thirty three goats were euthanized 10 to 300 min before the study. First, in 3 goats air was administered into the left or right common carotid artery at dose of 60, 100 and 120 ml/kg, and after each dose PMCT was performed in later ...[more]