Ontology highlight
ABSTRACT:
SUBMITTER: Schlunk F
PROVIDER: S-EPMC6478448 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Schlunk Frieder F Böhm Maximilian M Boulouis Gregoire G Qin Tao T Arbel Michal M Tamim Isra I Fischer Paul P Bacskai Brian J BJ Frosch Matthew P MP Endres Matthias M Greenberg Steven M SM Ayata Cenk C
Stroke 20190501 5
Background and Purpose- Mechanisms contributing to acute hematoma growth in intracerebral hemorrhage are not well understood. Neuropathological studies suggest that the initial hematoma may create mass effect that can tear vessels in the vicinity by shearing, causing further bleeding and hematoma growth. Methods- To test this in mice, we simulated initial intracerebral hemorrhage by intrastriatal injection of a liquid polymer that coagulates upon contact with tissue and measured the presence and ...[more]