Ontology highlight
ABSTRACT:
SUBMITTER: Meyers C
PROVIDER: S-EPMC6478587 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Meyers Carolyn C Lisiecki Jeffrey J Miller Sarah S Levin Adam A Fayad Laura L Ding Catherine C Sono Takashi T McCarthy Edward E Levi Benjamin B James Aaron W AW
JBMR plus 20190227 4
Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair process gone awry and is a common complication of trauma and surgery. This comprehensive review seeks to synthesize the clinical, pathoetiologic, and basic biologic features of HO, including nongenetic and genetic forms. First, the clinical features, radiographic appearance, histopathologic diagnosis, and current met ...[more]