Ontology highlight
ABSTRACT:
SUBMITTER: Ramos EM
PROVIDER: S-EPMC6480353 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Alzheimer's & dementia : the journal of the Alzheimer's Association 20190125 4
<h4>Introduction</h4>Primary progressive aphasia (PPA) is a neurological syndrome, associated with both frontotemporal dementia and Alzheimer's disease, in which progressive language impairment emerges as the most salient clinical feature during the initial stages of disease.<h4>Methods</h4>We screened the main genes associated with Alzheimer's disease and frontotemporal dementia for pathogenic and risk variants in a cohort of 403 PPA cases.<h4>Results</h4>In this case series study, 14 (3.5%) ca ...[more]