Ontology highlight
ABSTRACT:
SUBMITTER: Cagnone M
PROVIDER: S-EPMC6480715 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
High-throughput 20190213 1
<b>:</b> The neutrophilic component in bronchiolitis obliterans syndrome (BOS, the main form of chronic lung rejection), plays a crucial role in the pathogenesis and maintenance of the disorder. Human Neutrophil Elastase (HNE), a serine protease responsible of elastin degradation whose action is counteracted by α1-antitrypsin (AAT), a serum inhibitor specific for this protease. This work aimed to investigate the relationship between HNE and AAT in bronchoalveolar lavage fluid (BALf) from stable ...[more]