Ontology highlight
ABSTRACT:
SUBMITTER: Eghrari AO
PROVIDER: S-EPMC6482941 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Eghrari Allen O AO Vasanth Shivakumar S Gapsis Briana C BC Bison Henry H Jurkunas Ula U Riazuddin S Amer SA Gottsch John D JD
Cornea 20180701 7
<h4>Purpose</h4>Alternative splice isoforms of TCF4, a gene implicated in Fuchs corneal dystrophy, have been identified in multiple human tissues outside of the eye. The aim of this study was to identify the transcriptional profile of TCF4 in the corneal endothelium.<h4>Methods</h4>We extracted RNA from the donor corneal endothelium and performed rapid amplification of cDNA ends. We tested the expression pattern of 1 newly identified isoform (7b) in a panel of cDNA derived from multiple human ti ...[more]