Ontology highlight
ABSTRACT:
SUBMITTER: Lyons CE
PROVIDER: S-EPMC6482956 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20180507 9
Several studies have investigated how lifetime cognitive engagement affects levels of amyloid-beta (Aβ) deposition in the brain. However, there has been some disagreement, leaving the relationship of cognitive activity (CA) to Aβ a largely open question. The present study investigated the relationship between CA, Aβ deposition, and glucose metabolism. One hundred nine cognitively normal participants underwent Pittsburgh Compound-B (PiB) and [<sup>18</sup>F]fluorodeoxyglucose-positron emission to ...[more]