Ontology highlight
ABSTRACT:
SUBMITTER: Bokor E
PROVIDER: S-EPMC6483251 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
PloS one 20190425 4
Aspergillus nidulans has three high mobility group box (HMGB) proteins, HmbA, HmbB and HmbC that are chromatin-associated architectural proteins involved in DNA-related functions. By creating and studying deletion strains in both veA+ and veA1 background, we have characterized the role of HmbA, HmbB and HmbC in sexual development. Expression of the mating-type MAT1-1 and MAT1-2 coding genes were found to be extremely down-regulated in all three mutants on day 4 of sexual development, which resul ...[more]