Dataset Information
Deferasirox for managing iron overload in people with thalassaemia.
Ontology highlight
ABSTRACT:
SUBMITTER: Bollig C
PROVIDER: S-EPMC6483623 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Deferasirox for managing iron overload in people with thalassaemia.
The Cochrane database of systematic reviews 20170815
<h4>Background</h4>Thalassaemia is a hereditary anaemia due to ineffective erythropoiesis. In particular, people with thalassaemia major develop secondary iron overload resulting from regular red blood cell transfusions. Iron chelation therapy is needed to prevent long-term complications.Both deferoxamine and deferiprone are effective; however, a review of the effectiveness and safety of the newer oral chelator deferasirox in people with thalassaemia is needed.<h4>Objectives</h4>To assess the ef ...[more]