Ontology highlight
ABSTRACT:
SUBMITTER: Kou Q
PROVIDER: S-EPMC6484843 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Kou Qiang Q Wang Zhe Z Lubeckyj Rachele A RA Wu Si S Sun Liangliang L Liu Xiaowen X
Journal of proteome research 20190128 3
Top-down mass spectrometry is capable of identifying whole proteoform sequences with multiple post-translational modifications because it generates tandem mass spectra directly from intact proteoforms. Many software tools, such as ProSightPC, MSPathFinder, and TopMG, have been proposed for identifying proteoforms with modifications. In these tools, various methods are employed to estimate the statistical significance of identifications. However, most existing methods are designed for proteoform ...[more]