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Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors.


ABSTRACT:

SUBMITTER: Riley P 

PROVIDER: S-EPMC6486203 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors.

Riley Philip P   Glenny Anne-Marie AM   Worthington Helen V HV   Littlewood Anne A   Fernandez Mauleffinch Luisa M LM   Clarkson Jan E JE   McCabe Martin G MG  

The Cochrane database of systematic reviews 20171128


<h4>Background</h4>Oral mucositis is a side effect of chemotherapy, head and neck radiotherapy, and targeted therapy, affecting over 75% of high-risk patients. Ulceration can lead to severe pain and difficulty with eating and drinking, which may necessitate opioid analgesics, hospitalisation and supplemental nutrition. These complications may disrupt cancer therapy, which may reduce survival. There is also a risk of death from sepsis if pathogens enter the ulcers of immunocompromised patients. U  ...[more]

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