Ontology highlight
ABSTRACT:
SUBMITTER: Riley P
PROVIDER: S-EPMC6486203 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Riley Philip P Glenny Anne-Marie AM Worthington Helen V HV Littlewood Anne A Fernandez Mauleffinch Luisa M LM Clarkson Jan E JE McCabe Martin G MG
The Cochrane database of systematic reviews 20171128
<h4>Background</h4>Oral mucositis is a side effect of chemotherapy, head and neck radiotherapy, and targeted therapy, affecting over 75% of high-risk patients. Ulceration can lead to severe pain and difficulty with eating and drinking, which may necessitate opioid analgesics, hospitalisation and supplemental nutrition. These complications may disrupt cancer therapy, which may reduce survival. There is also a risk of death from sepsis if pathogens enter the ulcers of immunocompromised patients. U ...[more]