MiR-455-5p Suppresses the Progression of Prostate Cancer by Targeting CCR5.
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ABSTRACT:
SUBMITTER: Xing Q
PROVIDER: S-EPMC6487172 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
MiR-455-5p Suppresses the Progression of Prostate Cancer by Targeting CCR5.
Xing Qianwei Q Xie Huyang H Zhu Bingye B Sun Zhiwei Z Huang Yeqing Y
BioMed research international 20190411
Accumulated evidence indicates that miR-455-5p functions as tumor suppressor in the progression of various cancers. However, the mechanism through which miR-455-5p influences the tumorigenesis of human prostate cancer (PCa) remains undetermined. In this study, reanalysis of data obtained from the Memorial Sloan Kettering Cancer Center showed that miR-455-5p can be used as biomarker for PCa diagnosis and predictor of poor prognosis. Functional assays indicated that miR-455-5p overexpression could ...[more]
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