Ontology highlight
ABSTRACT:
SUBMITTER: Zhu C
PROVIDER: S-EPMC6487730 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Zhu Chengpei C Wu Liangcai L Lv Yanling Y Guan Jinxia J Bai Xue X Lin Jianzhen J Liu Tingting T Yang Xiaobo X Robson Simon C SC Sang Xinting X Xue Chenghai C Zhao Haitao H
Molecular oncology 20190411 5
Most cases of hepatocellular carcinoma (HCC) are already advanced at the time of diagnosis, which limits treatment options. Challenges in early-stage diagnosis may be due to the genetic complexity of HCC. Gene fusion plays a critical function in tumorigenesis and cancer progression in multiple cancers, yet the identities of fusion genes as potential diagnostic markers in HCC have not been investigated. Here, we employed STAR-Fusion and identified 43 recurrent fusion events in our own and four pu ...[more]