Ontology highlight
ABSTRACT:
SUBMITTER: Fortner RT
PROVIDER: S-EPMC6488363 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Fortner Renée T RT Poole Elizabeth M EM Wentzensen Nicolas A NA Trabert Britton B White Emily E Arslan Alan A AA Patel Alpa V AV Setiawan V Wendy VW Visvanathan Kala K Weiderpass Elisabete E Adami Hans-Olov HO Black Amanda A Bernstein Leslie L Brinton Louise A LA Buring Julie J Clendenen Tess V TV Fournier Agnès A Fraser Gary G Gapstur Susan M SM Gaudet Mia M MM Giles Graham G GG Gram Inger T IT Hartge Patricia P Hoffman-Bolton Judith J Idahl Annika A Kaaks Rudolf R Kirsh Victoria A VA Knutsen Synnove S Koh Woon-Puay WP Lacey James V JV Lee I-Min IM Lundin Eva E Merritt Melissa A MA Milne Roger L RL Onland-Moret N Charlotte NC Peters Ulrike U Poynter Jenny N JN Rinaldi Sabina S Robien Kim K Rohan Thomas T Sánchez Maria-José MJ Schairer Catherine C Schouten Leo J LJ Tjonneland Anne A Townsend Mary K MK Travis Ruth C RC Trichopoulou Antonia A van den Brandt Piet A PA Vineis Paolo P Wilkens Lynne L Wolk Alicja A Yang Hannah P HP Zeleniuch-Jacquotte Anne A Tworoger Shelley S SS
International journal of cancer 20190114 1
Ovarian cancer risk factors differ by histotype; however, within subtype, there is substantial variability in outcomes. We hypothesized that risk factor profiles may influence tumor aggressiveness, defined by time between diagnosis and death, independent of histology. Among 1.3 million women from 21 prospective cohorts, 4,584 invasive epithelial ovarian cancers were identified and classified as highly aggressive (death in <1 year, n = 864), very aggressive (death in 1 to < 3 years, n = 1,390), m ...[more]