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Renal Sympathetic Denervation in Patients with Resistant Hypertension: A Feasibility Study.

ABSTRACT: Background/Aims:We assessed the feasibility of renal sympathetic denervation (RDN) treatment in patients with resistant hypertension using the Iberis® RDN system. This study was a prospective, multicenter, single-arm feasibility registry. Methods:We collected data from patients who underwent RDN treatment using the Iberis system. From November 2014 to February 2016, 16 patients from 6 centers in Europe were enrolled in this registry. Results:Consistent reductions in the 24-h systolic blood pressure (SBP) and diastolic blood pressure were obtained. At any follow-up point, more than 70% of the patients were responders. The change in the 24-h SBP at 1 month was strongly correlated with that at 12 months. Conclusion:The Iberis system is safe and effective in patients for the treatment of resistant hypertension. Furthermore, our results suggest that we can estimate the effect of RDN in the long term at the 1-month follow-up point using the 24-h SBP.

SUBMITTER: Kario K 

PROVIDER: S-EPMC6489090 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Renal Sympathetic Denervation in Patients with Resistant Hypertension: A Feasibility Study.

Kario Kazuomi K   Rumoroso Jose Ramon JR   Okawara Yukie Y   Pérez de Prado Armando A   Garcia Fernandez Eulogio E   Kagitani Hideaki H   Goicolea Gómez Francisco Javier FJ   Rodríguez Leor Oriol O   Stankovic Goran G  

Pulse (Basel, Switzerland) 20180725 3-4

<h4>Background/aims</h4>We assessed the feasibility of renal sympathetic denervation (RDN) treatment in patients with resistant hypertension using the Iberis® RDN system. This study was a prospective, multicenter, single-arm feasibility registry.<h4>Methods</h4>We collected data from patients who underwent RDN treatment using the Iberis system. From November 2014 to February 2016, 16 patients from 6 centers in Europe were enrolled in this registry.<h4>Results</h4>Consistent reductions in the 24-  ...[more]

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