Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Castaneda C
PROVIDER: S-EPMC6492661 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Sánchez-Castañeda Cristina C de Pasquale Francesco F Caravasso Chiara Falletta CF Marano Massimo M Maffi Sabrina S Migliore Simone S Sabatini Umberto U Squitieri Ferdinando F
CNS neuroscience & therapeutics 20170502 6
<h4>Aims</h4>To analyze brain functional connectivity in the somatomotor and default-mode networks (DMNs) of patients with Huntington disease (HD), its relationship with gray matter (GM) volume loss, and functional changes after pridopidine treatment.<h4>Methods</h4>Ten patients and ten untreated controls underwent T1-weighted imaging and resting-state functional magnetic resonance imaging (fMRI); four patients were also assessed after 3 months of pridopidine treatment (90 mg/d). The seed-based ...[more]