Ontology highlight
ABSTRACT:
SUBMITTER: Kenkel WM
PROVIDER: S-EPMC6494504 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Kenkel W M WM Perkeybile A-M AM Yee J R JR Pournajafi-Nazarloo H H Lillard T S TS Ferguson E F EF Wroblewski K L KL Ferris C F CF Carter C S CS Connelly J J JJ
Science advances 20190501 5
Oxytocin is used in approximately half of all births in the United States during labor induction and/or augmentation. However, the effects of maternal oxytocin administration on offspring development have not been fully characterized. Here, we used the socially monogamous prairie vole to examine the hypothesis that oxytocin exposure at birth can have long-term developmental consequences. Maternally administered oxytocin increased methylation of the oxytocin receptor (<i>Oxtr</i>) in the fetal br ...[more]