Entropic effects enable life at extreme temperatures.
Ontology highlight
ABSTRACT:
SUBMITTER: Kim YH
PROVIDER: S-EPMC6494508 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Entropic effects enable life at extreme temperatures.
Kim Young Hun YH Leriche Geoffray G Diraviyam Karthik K Koyanagi Takaoki T Gao Kaifu K Onofrei David D Patterson Joseph J Guha Anirvan A Gianneschi Nathan N Holland Gregory P GP Gilson Michael K MK Mayer Michael M Sept David D Yang Jerry J
Science advances 20190501 5
Maintaining membrane integrity is a challenge at extreme temperatures. Biochemical synthesis of membrane-spanning lipids is one adaptation that organisms such as thermophilic archaea have evolved to meet this challenge and preserve vital cellular function at high temperatures. The molecular-level details of how these tethered lipids affect membrane dynamics and function, however, remain unclear. Using synthetic monolayer-forming lipids with transmembrane tethers, here, we reveal that lipid tethe ...[more]
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