Ontology highlight
ABSTRACT:
SUBMITTER: Mori A
PROVIDER: S-EPMC6495572 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Mori Akihiro A Holdorf Amy D AD Walhout Albertha J M AJM
Genes to cells : devoted to molecular & cellular mechanisms 20170808 9
Reverse genetic screens by RNA interference (RNAi) in model organisms such as the nematode Caenorhabditis elegans have provided numerous insights into gene function, thereby connecting genotype to phenotype. However, genes that contribute only subtly are often missed because relatively large numbers of measurements and reliable quantification are required to overcome experimental and biological noise that may mask subtle phenotypic effects. Here, we address this challenge by focusing on two phen ...[more]