Identification of stathmin 1 expression induced by Epstein-Barr virus in human B lymphocytes.
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ABSTRACT:
SUBMITTER: Baik SY
PROVIDER: S-EPMC6496458 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
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Identification of stathmin 1 expression induced by Epstein-Barr virus in human B lymphocytes.
Baik S Y SY Yun H S HS Lee H J HJ Lee M H MH Jung S E SE Kim J W JW Jeon J P JP Shin Y K YK Rhee H S HS Kimm K C KC Han B G BG
Cell proliferation 20070401 2
<h4>Introduction</h4>The Epstein-Barr virus transforms resting B cells into proliferating lymphoblastoid cells, the origin of cell lines.<h4>Method and results</h4>Our cDNA microarray analyses led to the identification of 232 up-regulated and 112 down-regulated genes with more than a 3-fold difference in lymphoblastoid cell lines compared to resting B cells. The functional classification of these genes exhibited the distinct expression signature for cell proliferation, cell cycle and an immune r ...[more]
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